The actress, who stars alongside Demi Moore in the body horror film, says it took "probably a year" for her skin to recover.

Hollywood star Margaret Qualley has revealed that the prosthetics she wore in the critically-acclaimed horror movie “The Substance” caused so much damage to her skin that it took about a year to recover.

In an interview on the podcast Happy Sad Confused, actress Margaret Qualley shared that the prosthetics she wore for the movie "The Substance" caused her face to break out in "absurd" acne.

What was not particularly intended to be a box office blockbuster has become very much so, and both the Maid actress and her co-star Demi Moore have enjoyed plenty of awards season buzz, with the latter earning her first major Hollywood award after over 40 years in the industry.

"It took me probably, like, a year to recover physically from all of it," she told a podcast about the prosthetics used in the film.

The actress spoke about dealing with acne caused by the movie makeup on Josh Horowitz's 'Happy Sad Confused' podcast

Margaret Qualley is opening up about the long-lasting effects she suffered while filming for 'The Substance.' The actress, who plays Sue in the body horror film, recently shared on the Happy Sad Confused podcast that her skin was damaged for nearly a year after filming wrapped.

During the ceremony, she presented an award with her Substance costar, Demi Moore. Qualley was also nominated for Best Supporting Female Actor, Film, for The Substance, but the trophy went to Zoë Saldaña for her role in Emilia Pérez. A winning night for women supporting women in Hollywood, indeed.

While Margaret Qualley has garnered high praise for her performance in 2024’s The Substance, she has revealed that the extensive amount of prosthetics that were required for the film took a toll on her skin.