Activated when cellular energy supplies are low, AMPK also functions at the whole body level to regulate metabolism and energy balance. ... mTOR-p70S6 kinase and AMPK pathways play distinct and ...

5′-AMP-activated protein kinase (AMPK) controls many cellular processes, particularly pathways involved in cellular energy status. 1 AMPK is activated during metabolic stress, and not only ...

Caffeine activates cell survival pathways in yeast, potentially slowing aging through energy and stress responses.

Your morning coffee may offer more than just a quick jolt of alertness. New research from Queen Mary University of London reveals caffeine's remarkable ability to extend the lifespan of cells by ...

In the complex chain of molecular events that underlie eating behaviors and body weight, the AMP-activated protein kinase (AMPK) enzyme has proven to be a critical link. Now, researchers at Beth ...

As a cellular energy sensor responding to low ATP levels, AMPK activation positively regulates signaling pathways that replenish cellular ATP supplies, including fatty acid oxidation, and autophagy.

Nowadays, the prevalence of sedentary lifestyles and high-caloric diets leads to an imbalance between energy intake and spending. Hence, in the last decades, we have observed a significant rise in ...

Although SOX9 has been implicated in regulating lipid metabolism in vitro, ... Furthermore, SOX9 deletion inhibited AMPK pathway activation, while SOX9 overexpression enhanced it.