Plants make a surprising intermediate en route to quinine and cinchonidine ...

Researchers found that gramine, a natural indole alkaloid, selectively inhibits triple-negative breast cancer by inducing ferroptosis. It directly binds CUL3, reducing MTDH ubiquitination and ...

In the realm of organic chemistry, one class of compounds has captured the scientific community's attention for decades - alkaloids. These naturally occurring compounds are known for their diverse ...

Alkaloids, which include caffeine and morphine, are a large class of pharmacologically active plant compounds that are often difficult to chemically synthesize. Incorporation of benzylisoquinoline ...

Plant-produced pyrrolizidine alkaloids (PAs) pose health risks due to their toxicity and frequent occurrence in foods like ...

Researchers report the first successful microbial biosynthesis of the tropane alkaloids hyoscyamine and scopolamine, a class of neuromuscular blockers naturally found in plants in the nightshade ...

Since the early 1800s, practitioners of organic chemistry have been fascinated with a group of plant-derived compounds called "alkaloids." Alkaloids contain at least one nitrogen atom among other ...

Scientists have identified 17 bioactive compounds in winter snowdrops, the earliest flowering plants in Europe. Out of the alkaloids identified, three are new to science and belong to a group with ...

A family of naturally occurring plant compounds could help prevent or delay memory loss associated with Alzheimer's disease, according to a new study. A family of naturally occurring plant compounds ...