The connection between perturbations in BBB barrier function and damage to the astrocyte network and its functions arises from BBB damage, leading to the extravasation of albumin. In the physiological ...

Increased expression of the Ang‐II (Angiotensin II) precursor AGT in aged astrocytes lead to increased Ang‐II signaling from aged astrocytes to endothelium, thus increasingblood–brain barrier (BBB) ...

Researchers at the Center for Neuroscience Imaging Research within the Institute for Basic Science (IBS) have uncovered a two-step mechanism by which the brain regulates blood volume—a breakthrough ...

A fall on the head, a blow to the skull, or a road traffic accident—the causes of traumatic brain injury are diverse, but the ...

The blood-brain barrier protects the central nervous system by tightly regulating what crosses between the two compartments. Neurons are vulnerable if the barrier suffers damage or weakens with age, ...

Resting brain stem cells hardly differ from normal astrocytes, which support the nerve cells in the brain. How can almost identical cells perform such different functions? The key lies in the ...

A project led by Johns Hopkins University has successfully imaged astrocytes, the brain's most abundant cells, in their natural state. The star-shaped astrocytes are known to be responsible for ...

Researchers at the Icahn School of Medicine at Mount Sinai say they have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via intravenous injection, a ...