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Antibody feedback reshapes B cell selection during immune response
A collaborative study published in Immunity from the Batista Lab and Liu Lab at the Ragon Institute, together with the Schief Lab at Scripps Research Institute, has uncovered a previously unrecognized ...
Janux Therapeutics has dosed the first participant in a Phase I clinical trial of JANX011, a Cluster of Differentiation 19 ...
The authors found that Csk (a tyrosine kinase that attenuates B cell receptor signaling) is required for germinal center maintenance and efficient antibody maturation. Osaka, Japan – The immune system ...
Researchers at the Ragon Institute and Scripps Research Institute have discovered that antibodies produced during immune responses act as a "brake" on B cell selection, preventing over-optimization ...
Scientists discovered which tumor cells resist treatment and why. By characterizing B-cells' developmental stages, they designed and tested a drug combination to effectively treat resistant B-cell ...
Technology based on Bracco’s clinically validated microbubble technology enables gentle, scalable cell selection and activation, streamlining workflows for cell therapy Bracco’s microbubbles, an ...
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