CD8 + T-cells are cytotoxic immune cells that can kill cancer cells, as well as cells infected with viruses or bacteria. These specialized T-cell express receptors that recognize specific antigens ...

Triple-negative breast cancer, an aggressive type of breast cancer, accounts for 10% of all breast cancer cases in the United ...

Tumor cells engineered to secrete anticancer agents yet resist self-destruction can be used to kill tumors in mice and then, in a fate befitting this act of betrayal, off themselves. “This is an ...

CD8 T cells lacking Tet1/3 preferentially differentiate into short-lived effector and effector memory cells following acute ...

which harnesses the immune system to attack and kill the body’s own cells. In recent years, biologists have begun to investigate whether activating necroptosis in cancer cells could similarly coax the ...

In primary T cells, TNFRSF25 agonists enhance survival, proliferation, and effector functions, including cytokine release and targeted cell killing ... tumor-antigen-driven ‘memory’ CD8 ...

A groundbreaking study published in Research (2025, DOI: 10.34133/research.0545) has elucidated the molecular mechanisms by which protein phosphatase 2A (PP2A) regulates CD8+ T cell-mediated immune ...

NEW YORK - A Ludwig Cancer Research study has identified a key barrier to the efficacy of a promising combination of ...