Here, the authors identify the chloride channel ANOH-1/ANO1 as a core component of a mechanosensory channel complex, highlighting its evolutionary conservation.
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NMD Pharma gets FDA IND clearance for Phase IIb gMG treatment trialA muscle-targeted small molecule inhibitor specifically targeting the ClC-1 chloride ion channel in skeletal muscles, NMD670 is being developed to alleviate persistent or fluctuating symptoms in ...
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Nanostructures in the deep ocean floor hint at life's originHowever, at nanopores with calcium adhered to the surface, the pores only allowed negative chloride ions to pass through. "The spontaneous formation of ion channels discovered in deep-sea ...
These molecules bind and block chloride-ion channels found in the neuronal cells of animals, including humans. The specific arrangement of atoms in the picrotoxane scaffold matters; for example ...
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