The treatment of acute lymphoblastic leukemia in adults is extremely complex ... The European LeukemiaNet (ELN) published its findings as a two-part special report in Blood Journal.

CCyR: Complete cytogenetic remission; CML: Chronic myeloid leukemia; CP: Chronic phase; ELN: European Leukemia Net; GIMEMA: Gruppo Italiano Malattie Ematologiche ...

Various clinical trials have evaluated the clinical value of an initial dose intensification of imatinib in CML-CP patients (an overview of the most important response rates is given in Table 1).