Edited by: Karen Young Kreeger M.S. Marber, R. Mestril, S.-H. Chi, M.R. Sayen, D.M. Yellen, W.H. Dillman, "Overexpression of the rat inducible 70-kD heat stress protein in a transgenic mouse increases ...

From molecular chaperones to mitochondrial failure, discover how heat reshapes the human transcriptome and drives the biological cascade that links rising temperatures to organ injury and public ...

(L to R) Corresponding author Charalampos Babis Kalodimos, PhD, St. Jude Department of Structural Biology chair, and co-first authors Ziad Ibrahim and Youlin Xia, St. Jude Department of Structural ...

The first full-length structures of two heat shock chaperone proteins in a complex reveal the key structural region regulating their function, according to a new study from St. Jude Children's ...

The exposure to low doses of stress induces an adaptive survival response that involves the upregulation of cellular defense systems such as heat shock proteins (Hsps), anti-apoptosis proteins, and ...