Hepatic LDL receptor and HMG-CoA reductase were both increased by 3- and 3.5-fold, respectively. No accumulation of cholesterol or triglycerides in the liver was noted, suggesting steatosis may ...
but other abnormalities due to lack of LDL receptors include altered hepatic cholesterol trafficking, increased apoB turnover, increased lipoprotein(a) and possibly decreased transintestinal ...
When your diet is high in saturated fat, the liver's LDL ("bad" cholesterol) receptors get overworked and LDL can't be ...
Their role is to transport cholesterol from the liver to the rest of the body and ... by a negative feedback system: cells have LDL receptors on their surface which allow cholesterol to be ...