Thousands of bacterial and other microbial species live in the human gut, supporting healthy digestion, immunity, metabolism and other functions. Precisely how these microbes are protected from immune ...

Tolerance to food begins to develop in the womb as the fetus’s immune system is exposed to substances derived from food consumed by the mother. It continues to mature while she nurses the baby and as ...

Sakaguchi's 1995 discovery of regulatory T cells revealed a complex immune tolerance system beyond central tolerance. Brunkow and Ramsdell identified the Foxp3 gene mutation in 2001, linking it to ...

Please provide your email address to receive an email when new articles are posted on . “[This honor] was a recognition of all of the work that the lab has done over the past 5 years,” Brown, ...

Study reveals how immune cells in the gut distinguish between food and harmful pathogens, shedding light on the origins of both food allergies and intestinal diseases. With every bite of food we take, ...

Discover how Treg cell therapies rethink precision medicine for autoimmune diseases like type 1 diabetes, MS, and transplant rejection.

Engineering regulatory T cells (Tregs) has emerged as a powerful strategy to achieve durable, antigen-specific immune tolerance for autoimmune and ...