Research has shown that dopamine (DA) plays a key role in how the body regulates the production of insulin. Typically, insulin is secreted by beta-cells in the pancreas in response to glucose—a ...
Diabetes is a lifelong, chronic health condition caused by abnormalities in the body’s production and use of the hormone insulin. Research has shown that the feel-good hormone, dopamine (DA), plays a ...
Researchers used an ultra-thin electronic mesh to stimulate lab-grown pancreatic cells, improving maturation and insulin ...
Type 2 diabetes (T2D) is characterized by persistent hyperglycemia (high glucose in blood) that leads to hypoxia (low oxygen condition) in pancreatic β-cells. T2D is a chronic metabolic disorder that ...
After an initial chemical screening, researchers at the University of Pennsylvania and Weill Cornell Medicine identified the Chk1/Chk2 dual inhibitor AZD-7762 among the strongest to induce insulin ...
Between 2016 and 2022, the researchers measured insulin secretion in response to carbohydrates (glucose), proteins (amino acids), and fats (fatty acids) from pancreatic islet cells taken from 140 ...
Tirzepatide, a drug approved for diabetes and on the fast track for approval as a weight loss therapy, works through a unique ability to activate two different mechanisms the body uses to control ...
The gene BHLHE40 disrupts insulin secretion in hyperglycemia-induced hypoxic conditions, which could inform drug development for type 2 diabetes Type 2 diabetes (T2D) is a chronic metabolic disorder ...
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