The aim of this study was to determine the effect of platelets on myoblast proliferation and differentiation in vitro and establish the role of platelets in skeletal myogenesis using murine muscle ...

Scordilis’ research interests are in molecular physiology, myogenesis and sexual dimorphism of skeletal muscle. Ordered, regulated movement is one of the distinguishing characteristics of life. In ...

Using adipogenesis and myogenesis as model systems, we show that MLL4 exhibits cell-type- and differentiation-stage-specific genomic binding and is predominantly localized on enhancers. MLL4 ...

Furthermore, we identified that a perimysial regulator Creb5 cooperates with TGF-β signaling to co-activate the expression of specific perimysial-to-myogenic signals such as Fgf18 to regulate ...

Methods Candidate genes and proteins regulating muscle protein breakdown (ubiquitin proteasome pathway), muscle protein synthesis (phosphatidylinositol 3 kinase/Akt/mammalian target of rapamycin ...