Recent studies are, however, illustrating that three different mechanisms of airflow obstruction play a role in COPD pathogenesis. The first is the loss of support of the small airways in ...

Besides metabolic disorders, microorganisms and their metabolites also play a key role in COPD pathogenesis. Individuals with ...

Pulmonary arterial hypertension (PAH) is an increasingly understood disease, with the genetics and pathophysiology mapped out to the extent that new therapies are emerging.1 The epidemiology, however, ...

And COPD also costs the health care system more ... talking about the disease, learning its pathophysiology. But let's be practical. A lot of folks who have lung disease or caregivers of those ...

Preclinical data had suggested reducing serotonin might improve symptoms of pulmonary arterial hypertension, but new phase 2b ...

Medically reviewed by Jeffrey S. Lander, MDMedically reviewed by Jeffrey S. Lander, MD Congestive heart failure (CHF), also ...

A pulmonary bleb is a small collection of air between the ... New York: The McGraw-Hill Company, 2009. Ohata M, Suzuki H. Pathogenesis of spontaneous pneumothorax: With special reference to the ...

Using Mendelian randomization analysis, researchers found evidence that 2 small groups of immunophenotypes are linked to either greater or lesser odds of developing pulmonary arterial hypertension ...

Over the last decade, as other companies—such as AstraZeneca with IL-5 inhibitor Fasenra—struggled to advance candidates for COPD, Regeneron and Sanofi took a more “phenotype-driven approach ...

The prophylactic vaccine BCG (Bacille Calmette-Guerin), fails to protect against the most common form of disease, adult pulmonary tuberculosis, and its efficacy varies dramatically e.g., from 0% in ...

Introduction Fluoroquinolones can cause severe collagen-associated adverse effects, potentially impacting the pulmonary ...

or heartburn seems to correlate with the development of COPD exacerbations, [20] a factor that was previously studied in asthma. The pathogenesis of this is poorly understood, but may be related ...