Three specific genes on chromosome 21 drive widespread brain changes in Down syndrome, uncovering a new framework for potential future treatment strategies.

Researchers at the Johns Hopkins Kimmel Cancer Center and its Ludwig Center uncovered new evidence that extra copies of a ...

The Y chromosome is among the smallest in the human body and carries the fewest genes. Researchers are paying renewed attention to its role in cancer—specifically, what happens when it vanishes.

New @hopkinskimmel research finds extra copies of chromosome 1q may drive the earliest stages of pancreatic cancer. › ...

Cutting-edge gene editing technology could eradicate Down syndrome, according to Japanese scientists. Down syndrome, which causes a range of developmental differences and affects 1 in 700 newborns in ...

Scientists in Japan have used gene-editing technology to remove the extra chromosome responsible for Down syndrome, at least in lab-grown human cells. The project, led by Dr. Ryotaro Hashizume of Mie ...

Scientists from Duke-NUS Medical School, working with collaborators at Imperial College London and partners in Europe and the United States, have uncovered new insights into how an additional copy of ...

When Addie was born with Down syndrome, her mom was overwhelmed with emotions. But now, she’s sharing a powerful message—one that’s changing how people see life with an extra chromosome. For National ...

Extra X chromosomes significantly increase the risk for systemic lupus erythematosus (SLE) and Sjögren disease, with the prevalence of these conditions being higher among patients with Klinefelter and ...

Gene editing techniques may eventually allow trisomy to be treated at the cellular level, according to an in vitro proof-of-concept study. Down syndrome is caused by the presence of a third copy of ...