These data will be matched with data from species across animal taxa in collaboration with the 11 IISAGE PIs. Epigenetic regulation of myogenesis is regulated by specific nutrients, namely amino acids ...

Scordilis’ research interests are in molecular physiology, myogenesis and sexual dimorphism of skeletal muscle. Ordered, regulated movement is one of the distinguishing characteristics of life. In ...

In fact, mice homozygotic for a PAX3 deletion do not develop muscles, demonstrating a central role of this gene in myogenesis. The clinical relevance is the severe phenotype observed in ...

Pancreatic cancer-associated muscle atrophy is characterized by strong mitochondrial metabolic defects that are not limited to carbohydrate, protein, and redox metabolism, but also concern lipid and ...