The six-subunit ORC is essential for the initiation of DNA replication in eukaryotes. Cancer cell lines in culture can survive and replicate DNA replication after genetic inactivation of individual ...

The six subunit ORC is essential for initiation of DNA replication in eukaryotes. Cancer cell-lines in culture can survive and replicate DNA replication after genetic inactivation of individual ORC ...

Recent papers published in Nature and Nature Astronomy found life’s building blocks on a near-Earth asteroid named Bennu.

Histone variants are non-canonical (non-allelic) variants of histones – representing one or a few amino acid differences – that are expressed at very low levels compared with their ...

Amino acid sequences are listed in Appendix Table S3. Finally, that this process relies on the co-option of host motifs by SteE suggests the intriguing possibility that eukaryotes might use kinase ...

Computer simulations help materials scientists and biochemists study the motion of macromolecules, advancing the development of new drugs and sustainable materials. However, these simulations pose ...

The NCBI Prokaryotic Genome Annotation Pipeline is designed to annotate bacterial and archaeal genomes (chromosomes and plasmids). Genome annotation is a multi-level process that includes prediction ...

This research was funded by the Department of Defense Ovarian Cancer Research Program (W81XWH-20-1-0816), Fred and Pamela Buffett National Cancer Institute Cancer Center Support Grant (P30CA036727), ...

This is an important textbook for undergraduate and graduate students in structural biology, chemistry, biochemistry, biology and medicine. Written by a team of leading scientists in the field, it ...

The mitochondrial genome is the full genetic complement of a mitochondrion. Mitochondrial DNA is only a small portion of the total DNA of a eukaryotic cell and in most species is solely inherited ...

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