Aging is a major risk factor for chronic diseases, and calorie restriction (CR) is a robust non-pharmacological intervention that can extend health ...

Milestone marks the first clinical program for Charcot-Marie-Tooth disease and Vanishing White Matter disease.

RTX-117 is an investigational small molecule designed to modulate the Integrated Stress Response (ISR) pathway, with the goal ...

Thanks to advances in imaging and diagnostic technologies, clinicians can now detect many genetic disorders in the womb, ...

This study presents valuable findings implicating nuclear export in the regulation of protein condensate behaviour and TDP-43 phase behaviour, suggesting a link to pathogenic aggregation in ALS/FTD.