Surprisingly, we found that APP induced dendritic spine loss only when co-expressed with BACE1. This effect was mediated by β-CTF, a β-cleavage product of APP, through an endosome-related pathway ...

In the United States, the Food and Drug Administration (FDA) does not regulate dietary supplements the way it regulates prescription medications. As a result, some supplement products may not contain ...

β-glucan has been characterized as a potent inducer of central trained immunity by reprogramming hematopoietic stem cells (HSCs) in the bone marrow. In the present study, we show that systemic ...

Functional assays including cell proliferation, scratch wound, tube formation, NO content detection, and senescence‐associated β‐galactosidase staining were conducted. RNA sequencing was performed to ...

School of Chemistry, Chemical Engineering and Life Sciences, Wuhan University of Technology, Wuhan 430070, People’s Republic of China ...

The Warhammer 40k Space Marine 2 Trygon update 7.0 patch notes are here, and there is truly far too much to read at once. The developers have been working hard, and the length of the patch notes ...

“Fast Regeneration 2” (Artificer tier): Completely reworked, the new perk is “Recoupment”: Killing a Majoris-level or higher enemy with a headshot with this weapon restores 1 Armour Segment. Cooldown ...

“Fast Regeneration 2” (Artificer tier): Completely reworked, the new perk is “Recoupment”: Killing a Majoris-level or higher enemy with a headshot with this weapon restores 1 Armour Segmen ...