The Cardinals beat the 49ers, 24-23, on Sunday afternoon in Santa Clara, a win that changed the outlook of their season.

If you told them it included wins over the San Francisco 49ers and Los Angeles Rams, most Cardinals fans would have rejoiced.

According to the latest odds available at DraftKings Sportsbook, the Seahawks are three-point underdogs at home for this week ...

Tom Brady reminisced on facing San Francisco 49ers quarterback Brock Purdy in 2022, the final season of his career.

With the San Francisco 49ers (2-3) and the Seattle Seahawks (3-2) squaring off on Oct. 10 at Lumen Field, Brock Purdy and ...

Two weeks after faltering on the road to the Los Angeles Rams, the 49ers blew another 10-point lead and exited with a 24-23 ...

The defense wilted in the heat, the offense couldn’t finish drives or protect the ball and the San Francisco 49ers blew ...

Here’s what fans and analysts were saying on Twitter after the 49ers dropped a shocking loss to the Cardinals in Week 5.

It was a good day for the future of the Las Vegas Raiders. Not because of what happened in their matchup against the Denver ...

San Francisco 49ers running back Christian McCaffrey won't return in Week 6, but will likely make his long-awaited comeback ...

This marked the second time this season that San Francisco (2-3) blew a double-digit lead in the fourth quarter to a division ...

With Moody sidelined, the 49ers had to pivot to a backup kicker. San Francisco has punter Mitch Wishnowsky serve as their ...