This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) license.
1Combination Strategies for Translational Immunotherapy, Immunology and Immunotherapy Program, Centro de Investigación Médica Aplicada (CIMA) Universidad de Navarra, Pamplona, Spain. 2Department of ...
1Department of Biology, University of Rochester, Rochester, New York. Search for other works by this author on: 2Westlake Disease Modeling Lab, Westlake Laboratory of Life Sciences and Biomedicine, ...
Department of Pathology, St. Jude Children’s Research Hospital, Memphis, Tennessee. *Corresponding Author: Brent A. Orr, Department of Pathology, St. Jude Children ...
Copyright held by the owner/author(s). This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International ...
Three cancer drugs separately earned FDA approval: The KRAS inhibitor sotorasib (Lumakras; Amgen) was approved for use with the EGFR inhibitor panitumumab (Vectibix; Amgen) to treat patients with ...
3Center for Neuro-Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts. *Corresponding Author: David A. Reardon, Center for Neuro-Oncology, Dana-Farber Cancer Institute, Boston, MA 02215.
Major Finding: Elevated bile acids (BA) in liver cancer contribute to T-cell dysfunction. Concept: BA accumulation in T cells promotes ER stress, reducing effector function and viability. Impact: ...