The Role of the Transcription Factor CREB in Immune Function
CREB is a transcription factor that regulates diverse cellular responses, including proliferation, survival, and differentiation. CREB is induced by a variety of growth factors and inflammatory …
CREB - Wikipedia
The function of CREB can be modulated via a signalling pathway resulting from the binding of serotonin and noradrenaline to post-synaptic G-protein coupled receptors. Dysfunction of …
What turns CREB on? And off? And why does it matter?
Apr 28, 2020 · Altered expression and function of the transcription factor cyclic AMP response-binding protein (CREB) has been identified to play an important role in cancer and is …
CREB Signaling in Neurons | GeneGlobe - Qiagen
Are you researching molecular biology of CREB Signaling in Neurons? Check out the QIAGEN pathway database for relevant molecules interactions. 🧬 Master GeneGlobe with step-by-step …
CREB: A multifaceted transcriptional regulator of neural and …
Feb 1, 2024 · In the CNS, regulation of physiological and pathological functions relies on various cell signaling and transcription programs. At the core of these events lies the cyclic adenosine …
Complex roles of cAMP–PKA–CREB signaling in cancer
Nov 24, 2020 · Cell growth is tightly regulated by a variety of signal transduction pathways. Abnormal activation or inhibition of signal transduction pathways drives tumorigenesis. …
Complex roles of cAMP-PKA-CREB signaling in cancer
Nov 24, 2020 · This review highlights the important roles of cAMP-PKA-CREB signaling in tumorigenesis. The potential strategies to target this pathway for cancer therapy are also …
Transcriptional regulation by the phosphorylation-dependent factor CREB …
Aug 1, 2001 · CREB is phosphorylated in response to various signals, but how is specificity achieved in these signalling pathways? Phosphorylation is a prevalent mechanism by which …
cAMP Response Element-Binding Protein (CREB): A Possible Signaling …
Recent studies propose that CREB is involved in signaling pathways leading to pathogenesis and therapy of certain mental disorders, including schizophrenia, making CREB an important focus …
A functional analysis of the CREB signaling pathway using …
Oct 27, 2009 · In this study we finely map the genome-wide targets of the CREB protein across all known and predicted human promoters, and characterize the functional consequences of a …
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