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Archives of Disease in Childhood is an international peer review journal that aims to keep paediatricians and others up to date with advances in the diagnosis and treatment of childhood diseases as well as advocacy issues such as child protection.
What’s new in the management of neonatal early-onset sepsis?
The expert guidelines highlighted in this review provide an evidence-based framework for approaching at-risk infants and allow for a more limited and standardised approach to antibiotic use. While these guidelines have significantly reduced antibiotic utilisation worldwide, optimally each unit would individualise their approach to early onset sepsis (EOS) based on the neonatal population they ...
Homepage | ADC Fetal & Neonatal Edition
3 days ago · Archives of Disease in Childhood is led by Dr Nick Brown, clinician, epidemiologist and international child health expert. His vision is to enhance child health through training, advocacy, and publishing high quality research that will influence policy, and to do all this “with passion, wit and flavour”.
Nucleated red blood cells in the fetus and newborn
Although nucleated red blood cells (nRBCs) are rarely found circulating in older children,1 they are commonly seen in the blood of newborns. They are primarily produced in the fetal bone marrow in response to erythropoietin and are stored in the marrow as precursors to reticulocytes and mature erythrocytes. Many acute and chronic stimuli cause increases in the number of circulating nRBCs from ...
Survival and unique clinical practices of extremely preterm infants ...
Objectives To investigate prognosis and clinical practices of infants born at 22–23 weeks’ gestational age (wkGA) in Japan. Design A national institutional-level electronic questionnaire surveys performed in September 2021. Setting All perinatal centres across Japan. Patients Infants born at 22–23 wkGA in 2018–2020. Main outcome measures Proportion of …
Neonatal thrombocytopenia: causes and management
Neonatal thrombocytopenia is a common clinical problem. Thrombocytopenia presenting in the first 72 hours of life is usually secondary to placental insufficiency and caused by reduced platelet production; fortunately most episodes are mild or moderate and resolve spontaneously. Thrombocytopenia presenting after 72 hours of age is usually secondary to sepsis or necrotising enterocolitis and is ...
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About | ADC Fetal & Neonatal Edition
The content of ADC Fetal & Neonatal is endorsed by the Royal College of Paediatrics and Child Health for Continued Professional Development in line with RCPCH CPD guidelines. ADC Fetal & Neonatal has an open access companion journal, BMJ Paediatrics Open.For information about the Editor-in-Chief and editorial team, please refer to the Editorial Board page.
Understanding the principle biophysics concepts of pulmonary …
Pulmonary surfactant (PS) is a lipid-protein complex essential to stabilise the delicate structure of mammalian alveoli along with successive compression-expansion respiratory cycles. To do so, surfactant reduces dramatically surface tension at the air-liquid interface, an activity that depends critically on a proper lipid composition and the presence of some specific surfactant proteins. Lack ...
Table of contents - ADC Fetal & Neonatal Edition
Apr 18, 2024 · Diagnosis and management of congenital diaphragmatic hernia: a 2023 update from the Canadian Congenital Diaphragmatic Hernia Collaborative (25 October, 2023) Free