Clinician Insights on How to Manage Semaglutide-Induced …
Sep 8, 2023 · Patients who receive treatment with a glucagon-like peptide-1 (GLP-1) receptor agonist, such as semaglutide, may experience delayed gastric emptying due to the drug’s mechanism of action (MOA). 1 Symptoms may include nausea, vomiting, heartburn, pain, or bloating. 2 However, the symptoms of delayed gastric emptying resulting from GLP-1 receptor agonists may be similar to symptoms of ...
What We Know About Semaglutide Adverse Events and …
Sep 1, 2023 · What Are Other Causes of Gastroparesis? Diabetes is the most common underlying cause of gastroparesis and can damage the vagus nerve, leading to impaired muscular function in the stomach and small intestine. 3 Studies show that the 10-year cumulative incidence of diabetic gastroparesis is estimated to be 5.2% among patients with type 1 diabetes and 1% in patients with type 2 diabetes. 4
Survival Has Improved Over Time for Patients With HCC
18 hours ago · Overall, 72.7% of patients died from any cause, and 52.6% died from HCC. The rate of all-cause mortality was significantly higher in era 1 than in era 2 (87.4% and 62.1%, respectively; P <.001). The rate of HCC-related mortality was significantly higher in era 1 than in era 2 as well (66.5% and 42.7%, respectively; P <.001). In a multivariable analysis, characteristics associated with ...
New Oral Tablet Prep for Colonoscopy: The Important Details
Feb 8, 2021 · Importance of Adequate Bowel Prep. From the perspective of the gastroenterologist, adequate bowel prep is crucial in screening colonoscopy, for which it is used to detect cancerous and precancerous lesions, and in diagnostic colonoscopy, such as that performed because of bleeding or diarrhea. Up to 25% of patients undergoing colonoscopy may ...
GLP-1 RA Use Linked to Retained Gastric Contents During …
18 hours ago · HealthDay News — Use of glucagon-like peptide 1 receptor agonists (GLP-1 RAs) is associated with the risk for retained gastric contents and inadequate bowel preparation during endoscopic procedures, according to a research letter published online Oct. 1 in JAMA Network Open.. Jason Nasser, M.D., from Cedars-Sinai Medical Center in Los Angeles, and colleagues examined the potential ...
Higher CCI Linked to In-Hospital Mortality After EUS-Guided PFC
18 hours ago · The relationship between CCI and in-hospital mortality risk was validated using data from patients (n=4053) who underwent EUS-guided treatment for PFCs. The WONDERFUL and DPC cohorts comprised 77% and 71% men, they had a mean [SD] age of 60.4 [13.7] and 62.8 [14.2] years, 85% and 80% had a BMI less than 25 kg/m 2, and 71% and 90% received a ...
Anti-TL1A Monoclonal Antibody, Tulisokibart, Aids Ulcerative Colitis
18 hours ago · HealthDay News — Tulisokibart, a tumor necrosis factor-like cytokine 1A monoclonal antibody, is more effective in inducing clinical remission in patients with moderately to severely active ulcerative colitis than placebo, according to a phase 2 study published in the Sept. 26 issue of the New England Journal of Medicine.. Bruce E. Sands, M.D., from the Icahn School of Medicine at Mount Sinai ...
Tradipitant Relieves Nausea, Other Gastroparesis Symptoms
Oct 27, 2022 · Tradipitant is efficacious for relieving nausea and other gastroparesis symptoms. Tradipitant significantly improved nausea and other symptoms in patients with idiopathic and diabetic gastroparesis compared with placebo, according to study results presented at the American College of Gastroenterology (ACG) 2022 Annual Meeting, held from October ...
Gastric Intestinal Metaplasia: 2020 AGA Guidelines
Gastric cancer (GCa) has a significant impact on worldwide morbidity and mortality as the third-leading cause of cancer death in the world. 1 It has traditionally been associated with poor outcomes and limited treatment options by the time patients clinically present. Helicobacter pylori (HP) is the primary cause of intestinal-type noncardia GCa (located in the antrum, body, incisura, or ...
Controversies in the Diagnosis and Treatment of Gastroparesis
In an editorial published by the American Journal of Gastroenterology, authors Brian E. Lacy, MD, PhD and David J. Cangemi, MD addressed common misconceptions regarding the diagnosis and treatment of gastroparesis (GP).The prevalence, etiology, and pathogenesis of GP were described, along with diagnostic techniques and prognosis.