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Why is the 2025 Nobel Prize the most important year in the history of modern science?
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TheTalas on Instagram: "The 2025 Nobel Prize in Physiology or Medicine was awarded not for a new drug or a single experiment, but for a fundamental explanation of why the immune system usually does not destroy the body it is meant to protect. For decades, immunology focused on how immunity attacks. What was missing was a clear answer to the opposite question: how immunity learns restraint. The laureates — Mary E. Brunkow, Fred Ramsdell, and Shimon Sakaguchi — solved this by uncovering the mechan
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TheTalas on Instagram: "The 2025 Nobel Prize in Physiology or Medi…
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Instagramthetalaslab
Regulatory T cells (Tregs) (CD4 CD25 FoxP3 ) are primarily targeted in cancer treatment to reverse their immunosuppressive effects within the tumor microenvironment, which allows tumors to escape immune surveillance. Strategies include depleting intratumoral Tregs, inhibiting their function, or modulating their metabolism to boost anti-tumor immune responses. Key aspects of Treg modulation in cancer treatment: Mechanism of Action: Tumors often show high infiltration of Tregs, which suppress effe
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Facebookrisesknowledge
Han pasado ya 30 años desde su descubrimiento y ayer recibieron el Premio Nobel. En 1995 Shimon Sakaguchi descubrió las células T reguladoras por primera vez, y en 2001 Mary Brunkow y Fred Ramsdell identificaron el gen FOXP3, clave para su desarrollo. #NobelMedicina2025 #Inmunología #nobel2025 #medicine #stem
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TikTokitsdramariafernanda
medicalmedia.kz on Instagram: "🏆 Нобелевская премия по медицине 2025 Три учёных получили Нобелевку за то, что раскрыли, почему иммунитет отличает “своё” от “чужого” — и почему иногда он атакует организм, вызывая аутоиммунные болезни. 🧬 В чём прорыв? Они изучили регуляторные T-клетки — главный «тормоз» иммунитета — и открыли ключевой ген FOXP3. Когда он ломается, иммунитет начинает разрушать собственные клетки. 🔬 Что это меняет? Их открытия стали основой будущих методов лечения: • диабета 1 ти
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📚 El Premio Nobel de Medicina 2025 confirmó algo fundamental para q…
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